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KMID : 0988920130110020127
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Intestinal Research
2013 Volume.11 No. 2 p.127 ~ p.133
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Clinical Characteristics of Lower Gastrointestinal Cancer in Crohn’s Disease: Case Series of 5 Patients
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Choi Ji-Min
Lee Chang-Hyun
Han Yoo-Min
Lee Min-Jong
Jang Ae-Ra
Kwon Jee-Hye
Im Jong-Pil
Kim Sang-Gyun
Kim Joo-Sung
Jung Hyun-Chae
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Abstract
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Crohn’s disease is a chronic inflammatory disease that can involve the entire gastrointestinal tract. Several studies indicate that Crohn’s patients with long disease duration have an increased risk of small bowel or colorectal cancer. In Korea, only a few cases of Crohn’s disease-related small bowel or colorectal cancer have been reported. Here, we described 3 cases of colorectal cancer and 2 cases of small bowel cancer in patients with Crohn’s disease. Among 5 patients, 3 had Crohn’s disease-related lower gastrointestinal malignancy and the other 2 had sporadic lower gastrointestinal malignancies. Since the diagnosis of Crohn’s disease-related lower gastrointestinal malignancy tends to be delayed, the development of malignancy should be considered in patients with long duration of Crohn’s disease if patients have refractory symptoms despite intensive medical treatment. Surgical consultation should not be delayed.
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KEYWORD
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Crohn disease, Jejunal neoplasms, Ileal neoplasms, Colorectal neoplasms
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